Gruppo di Studio sulla Ipertensione Arteriosa


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Forum redazionale sui Trials in Campo di Ipertensione e malattie Vascolari  

Società Italiana di Nefrologia

Gruppo di studio dell’Ipertensione Arteriosa


A cura di Alessandro Zuccalà per incarico del Direttivo del gruppo.

Trial in esame: NORDIL study

: Hansson L, Hedner T, Lund-Johansen P, Kjeldsen SE, Lindholm LH, Syvertsen JO, Lanke J, de Faire U, Dahlof B, Karlberg BE. 
Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet. 2000 Jul 29;356(9227):359-65


Trial in esame: Studio LIFE

: Lindholm LH, Ibsen H, Dahlof B, Devereux RB, Beevers G, de Faire U, Fyhrquist F, Julius S, Kjeldsen SE, Kristiansson K, Lederballe-Pedersen O, Nieminen MS, Omvik P, Oparil S, Wedel H, Aurup P, Edelman J, Snapinn S.
Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.
Lancet. 2002 Mar 23;359(9311):1004-10.


Gli articoli di NDT educational sull'Ipertensione recensiti dalla inesauribile Francesca Mallamaci

Serum Total Cholesterol Concentrations and Awareness, Treatment, and Control of Hypercholesterolemia Among US Adults: Findings From the National Health and Nutrition Examination Survey, 1999 to 2000. Circulation. 2003 May 6;107(17):2185-9.
Prospective investigation of autonomic nervous system function and the development of type 2 diabetes: the atherosclerosis risk in communities study, 1987-1998. Circulation. 2003 May 6;107(17):2190-5.
Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation. 2003 May 6;107(17):2207-12.
Comparison of 10-mg and 5-mg Warfarin Initiation Nomograms Together with Low-Molecular-Weight Heparin for Outpatient Treatment of Acute Venous Thromboembolism. A Randomized, Double-Blind, Controlled Trial. Ann Intern Med. 2003 May 6;138(9):714-9.
Maternal-fetal flow, negative events, and preeclampsia: role of ACE I/D polymorphism. Hypertension. 2003 Apr;41(4):932-7.
Prolonged QTc interval and high B-type natriuretic peptide levels together predict mortality in patients with advanced heart failure. Circulation. 2003 Apr 8;107(13):1764-9.
Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathing. JAMA. 2003 May 7;289(17):2230-7.
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. Lancet. 2003 May 3;361(9368):1511-1517.
Traditional and emerging cardiovascular risk factors in end-stage renal disease KI 2003; 63(s85): 105-110.
Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells. Circulation. 2003 May 13;107(18):2342-7.
Glomerular number and size in autopsy kidneys: The relationship to birth weight. KI 2003 Jun; 63(6): 2113-22.
Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes. Circulation. 2003 May 20;107(19):2435-9.
Simvastatin normalizes autonomic neural control in experimental heart failure. Circulation. 2003 May 20;107(19):2493-8.
A low-carbohydrate as compared with a low-fat diet in severe obesity. NEJM 2003 May 22; 348(21): 2074-81.
Renin-Angiotensin System and Atherothrombotic Disease: From Genes to Treatment AIM 2003;163:1155-1164.
Relationship Between Periodontal Disease and C-Reactive Protein Among Adults in the Atherosclerosis Risk in Communities Study AIM 2003;163:1172-1179.
Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA. 2003 May 14;289(18):2363-9.
BMP-7 Is an Efficacious Treatment of Vascular Calcification in a Murine Model of Atherosclerosis and Chronic Renal Failure. JASN 2003 Jun; 14(6): 1559-67.


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